Shawnee Tribe Breaks Ground on Expansion at Golden Mesa Casino GUYMON, Okla. Golden Mesa Casino is the exclusive gaming experience in the Oklahoma Panhandle – now open 24/7! Located just south of Guymon, OK, along Highway 54, Golden. Locations. Headquarters: GUYMON, Oklahoma. Hit the tables or the slots at Golden Mesa Casino in Guymon. This casino is very nice. Golden Mesa is a 37,square-foot facility on a acre site just southwest of Guymon, Oklahoma. Website: [HOST] External link for GOLDEN MESA CASINO. Visit · golden mesa casino winners. Only reason why I gave them a 4 star, and not a 5 is because they do not have a "non smoking section". Cigerette Smoke does. Pull up a seat and enjoy some of the region's hottest games, including Blackjack and Ultimate. Golden Mesa Casino, located along Highway 54, is the best gaming destination for the Oklahoma and Texas Panhandles, New Mexico, Colorado and Kansas regions. – Shawnee Tribe Chief Ben Barnes, along with tribal and local leaders and. Designed by Rees and Associates, the project design allows. MILE 28 RD. . GUYMON, Oklahoma , us. The Shawnee Tribe is proud of the partnership it's forged with the Chickasaw Tribe in bringing this destination Casino to Guymon Oklahoma.