Unfortunately, there are no casinos in Destin, Florida as of now. Top 10 Best Casinos in Destin, FL - April - Yelp - The Island Resort at Fort Walton Beach, Margaritaville - Destin, Wild Willy's Adventure Zone. casinos in Biloxi, MS nearly three hours away. The Best 10 Casinos near Destin, FL · The Island Resort at Fort Walton Beach · Margaritaville - Destin · Wild Willy's Adventure Zone · Mary Esther Bingo. In Destin, we want to keep Florida summers alive. Ebro Greyhound Park Poker Room · Dog Track Road ; Pensacola Greyhound Track & Poker Room · Dog Track Rd ; Wind Creek Casino & Hotel, Atmore. The closest casino would be the Wind Creek Casino and Hotel in Atmore, Alabama, approximately. Las Vegas-style. I think there is a poker room at a dog track in Ebro - there is a slots only casino in Atmore, AL about 2 hours away - table games available at. That's why we join the Florida Chamber in opposing Las Vegas- style casinos. . Another large shopping center in the Destin area is Destin Commons which features a large movie theater, department stores, restaurants, specialty shops and. Casinos Outdoors & Adventure Nature and Wildlife Preserves Forests Everglades National Park Dolphins Manatees Birding HOW TO MEET MANATEES IN FLORIDA.